University of Jordan

Traditional root canal therapy is effective in maintaining masticatory function and aesthetics in
the short term. However, endodontically-treated teeth lose their vitality and biological defense
mechanisms against microbial infections. This jeopardizes the long-term health and longevity of
these teeth.
Accordingly, new solutions in tissue engineering and regenerative therapy are needed to heal
pulpitis, restore the dental pulp’s homeostasis, or even replace the dental pulp with a new
engineered tissue. Dental pulp regeneration requires a combination of three components:
Scaffolds, growth factors, and stem cells. Scaffolds are biomaterials that create foundations for
the newly produced dental pulp. Growth factors are signaling molecules that enhance healing and
promote differentiation. Stem cells are undifferentiated or partially differentiated cells that form
the new dental pulp tissue.
This presentation will discuss the latest updates on dental pulp regeneration in dentistry using
regenerative methods. The main topic of discussion will be whether dental pulp regeneration is a
promising solution or an overhyped one. Additionally, the presentation will explore the potential
for dental pulp regeneration to become a routine procedure in the coming decades.